| Roche Molecular Biochemicals |
Category
 |
Product
 |
Specification
 |
| Cloning
and Fragmentation |
Restriction
Enzymes
(e.g.: restriction endonuclease Not I) |
Most
fundamental tools in modern life science research, enabling the basic cloning and initial
analysis of DNA fragments. 122 different enzymes are available. |
| Cloning
and Fragmentation |
Molecular
Weight Markers |
A broad
selection of size markers for the accurate determination of the molecular weight of DNA
and RNA fragments. |
| Cloning
and Fragmentation |
Modifying
Enzymes |
Modifying
enzymes used together with restriction enzymes during the cloning of DNA to recognise and
locate specific DNA or RNA fragments. |
| Protein
Analysis |
Protein
Purification
(e.g.: protease inhibitors) |
Products
used to isolate and analyse specific proteins or groups of proteins. |
| Protein
Analysis |
Protein
Sequencing |
Proteases,
that cleave proteins according to the amino acid sequence and enable the determination of
the sequence of these amino acids. |
| Protein
Analysis |
Glycan
Analysis |
Kits and
reagents for the analysis of the glycan structures. |
| General
Biochemicals |
Cell
Cultivation and Monitoring (e.g.: IL-2) |
Selection
of enzymes for tissue dissociation, growth factors and cytokines. Reagents for mycoplasma
detection and elimination. |
| General
Biochemicals |
Secondary
Detection |
Detection
system using two antibodies - one maximising the specificity to the target and the other
maximising the sensitivity of the signal. |
| General
Biochemicals |
Signal
Transduction |
Biological
tools (e.g. antibodies, enzymes, hormones) to study the communication and transduction of
signals among cells. |
| General
Biochemicals |
Metabolic
Enzymes |
They
enable researchers to study different pathways. |
| Cell
Isolation |
Liberase |
Liberase
is a defined mixture of highly purified bacterial enzymes, formulated for optimal
enzymatic isolation of islets from human, porcine, and canine pancreas. Used in diabetes
research. |
| BioMedicals |
Molecular
Pathology
(e.g.: Telomerase PCR ELISA) |
Test
kits and reagents for the detection of molecular targets in pathology. Used in basic and
clinical research studies in oncology, genetic diseases and infectious diseases. |
| BioMedicals |
ELISAs
for Medical Research |
Test
kits for the quantification of cytokines, growth factors and their receptors, cell
adhesion molecules and various neurological and oncological parameters in biological
fluids. |
| BioMedicals |
Pharmanalytics |
Life
sciences products and services for use in pharmaceutical drug development. Used in assays
development and high throughput screening, in pharmacology, toxicology, and in quality
control. |
| Apoptosis
and Cell Proliferation |
Apoptosis |
Tools
for the detection and characterisation of cell death. |
| Apoptosis
and Cell Proliferation |
Cell
Proliferation |
Cell
proliferation is the key to many biological processes and disease states. Our products
allow the monitoring of this process through a variety of methods. |
| Amplification
(PCR) |
Thermostable
Enzymes
(e.g.: Taq DNA Polymerase) |
High
performing products for Polymerase Chain Reaction (PCR) |
| Non-radioactive
Labelling and Detection |
DIG
System for Nucleic Acid Labelling and Detection
(e.g.: Anti-DIG-AP) |
Non-radioactive
nucleic acid labelling and detection for blot and in situ applications. This system is
based on the steroid hapten digoxigenin detected via an antibody reaction using
chemiluminescent substrates. |
| Non-radioactive
Labelling and Detection |
Protein
Labelling and Detection |
Based on
either biotin, digoxigenin or flourescein, our kits offer non-radioactive labelling and
detection of antibodies. For use in immunohisto/cytochemistry, western blots and ELISA
procedures. |
| Nucleic
Acid Purification and Isolation (NAPI) |
|
Reagents
and devices for the isolation and purification of DNA and RNA. |
| Gene
Function Analysis (Gene and Protein Expression) |
Epitope
Tagging |
Technologies
for tagging or labelling of recombinant proteins. Includes antibody vectors for detection,
quantification and purification. |
| Gene
Function Analysis (Gene and Protein Expression) |
Reporter
Gene Analysis |
Products
to measure model gene expression and regulation of expression. |
| Gene
Function Analysis (Gene and Protein Expression) |
Transfection
Reagents
(e.g. DOTAP) |
Unique
chemical tools for the introduction of foreign DNA and RNA into cells for the study of
expression and regulation. |
| Instrumentation |
Lumi-Imager |
An
instrument for the analysis and documentation of non-radioactively labelled biomolecules
which were visualised by using chemiluminescent substrates or flourescence. This
instrument enables high resolution imaging and the detailed, accurate quantitative and
qualitative evaluation of blots and gels. |
| Instrumentation |
LightCycler |
Innovative,
temperature-controlled fluorimeter for the on-line, real-time detection of PCR. Used for
on-line quantification of nucleic acid targets, mutation detection and sequence
confirmation. Used primarily in basic and clinical research studies in oncology, genetic
diseases, infectious diseases and in gene expression studies. |
| Industrial
Biochemicals |
Large
scale of biochemicals for the diagnostic and other industries. |
Enzymes,
Antibodies, Probes, Nucleotides, Carbohydrates, Biopharmaceuticals, Biocatalysts offered
as a raw material and finished products. |
| Roche Molecular Systems |
Category
 |
Product
 |
Specification
 |
Semi-automated
microwell plate assays
(manual test kits) |
AMPLICOR |
The
Roche brand name for the microwell plate PCR qualitative and quantitative assays. |
| Qualitative
assays |
HIV-1 |
Detects
the presence of HIV-1 viral components (proviral DNA) in the blood cells even before the
production of antibodies. |
| Qualitative
assays |
HCV -
hepatitis C virus |
Diagnostic
tool to confirm the presence of hepatitis C virus (HCV-RNA) in serum/plasma; determines
patient response to activiral therapy. |
| Qualitative
assays |
Others |
HTLV
I/II, CMV, Enterovirus, C. trachomatis, N. gonorrhoeae, M. tuberculosis, M. avium, M.
intracellulare. |
| Quantitative
assays |
AMPLICOR
HIV-1 MONITOR |
First
test approved worldwide to accurately and precisely measure the quantity of circulating
HIV-1 virus (HIV-RNA) in plasma. The test has been accepted by physicians and laboratories
as the most sensitive test to monitor HIV infected patients. |
| Quantitative
assays |
AMPLICOR
HCV MONITOR |
The most
sensitive test to measure the quantity of circulating hepatitis C virus (HCV-RNA) in
serum/plasma and to monitor patients' response to antiviral therapy. |
| Quantitative
assays |
AMPLICOR
HBV MONITOR |
Quantifies
the amount of hepatitis B virus (HBV-DNA) in serum or plasma. |
| COBAS
AMPLICOR |
|
The
COBAS AMPLICOR is the first system to automate both the amplification and detection steps
of the PCR testing process by combining five instruments into one (thermal cycler,
automatic pipettor, incubator, washer and reader). The system is a bench top system that
makes PCR testing a routine diagnostic, especially for the MONITOR (quantitative) tests.
The COBAS AMPLICOR automation maximises walkaway time, improves laboratory productivity
and assures result integrity. The software allows MultiPlex (multiple detections from an
amplified sample) and ReFlex (automated pre-selected next test detection) testing. The COBAS AMPLICOR amplifies and detects up to 24
samples simultaneously with parallel amplification and detection of up to 48 samples. Up
to six detections can be performed on each amplified sample, the system delivers 50
detection results per hour. For the MONITOR (quantitative) tests dilutions are performed
automatically onboard. |
|
Assays
for COBAS AMPLICOR |
Hepatitis
C, C. trachomatis, N. gonorrhoeae, M. tuberculosis, M. intracellulare, M. avium,
HCV MONITOR, HIV MONITOR, CMV MONITOR and HBV MONITOR plus Internal Control |
| Amplification
- Polymerase Chain Reaction (PCR) |
Thermostable
Enzymes
(e.g.: Taq DNA Polymerase) |
Enzymes
used for Polymerase Chain Reaction (PCR). |
| Roche Laboratory
Systems |
Category
 |
Product
 |
Specification
 |
| COBAS
INTEGRA line |
COBAS
INTEGRA 700 |
Random
and continuous access, sample selective analyser designed for medium and high-volume
laboratories. Integrates four measuring technologies: absorbance photometry, turbidimetry,
fluorescence polarisation and Ion Selective Electrode (ISE) potentiometry. The breadth of
test menu allows the system to effectively consolidate special tests or provide the
capability of full laboratory consolidation for clinical chemistry and homogeneous
immunoassays. Capacity of 72 tests onboard (including 4 ISE: Na, K, Cl and Li); up to 600
tests per hour, up to 855 tests per hour with electrolytes. |
| COBAS
INTEGRA line |
COBAS
INTEGRA 400 |
Same
features as Cobas INTEGRA 700, but a table top model with capacity of 36 tests on board
(including 4 ISE); up to 340 tests per hour, up to 460 tests per hour with electrolytes. |
| BM/Hitachi
line |
BM/Hitachi
902 |
Compact,
sample selective clinical chemistry analyser designed for small to mid-size workloads.
Capacity of 39 tests onboard (including 3 ISE); up 200 tests per hour, up to 300 tests
with optional ISE. |
| BM/Hitachi
line |
BM/Hitachi
912 |
Sample
selective analyser designed for mid-size workloads. Flexible system for the performance of
both classical and special clinical chemistries, homogeneous immunoassays, and STAT
analyses. Capacity of 35 tests onboard (including 3 ISE); up to 360 tests per hour, up to
720 tests with optional ISE. |
| BM/Hitachi
line |
BM/Hitachi
917 |
Sample
selective analyzer designed for medium to high workloads. Flexible system for the
performance of both classical and special clinical chemistries, homogeneous immunoassays,
and STAT analyses. Capacity of 48 tests onboard (including 3 ISE); up to 800 tests per
hour, up to 1200 tests with optional ISE. Sample carrier options include disc or Hitachi
5-position rack. |
| BM/Hitachi
line |
BM/Hitachi
747 |
Expandable,
sample selective clinical chemistry analyzer designed for very high workloads.
Available in two different configurations:
| 747/100 |
Capacity of 32 tests
onboard (with ISE 35 tests); up to 2400 tests per hour, up to 3300 tests per hour with
optional ISE. |
| 747/400 |
Capacity of 32 tests
onboard (with ISE 35 tests); up to 9600 tests per hour, up to 11400 tests per hour with
optional ISE. |
|
| BM/Hitachi
line |
MODULAR:
P 800; D 2400; ISE 900/1800; CA 300 |
Offers
expandable MODULAR automation for clinical chemistry and homogeneous immunoassays for
higher-volume workloads. Intelligent process/sample management and a variety of module
combinations. Future modules will include heterogeneous immunoassay testing using
electrochemiluminescence technology allowing customers to design their own serum work
area. The Hitachi 5-position rack is used as a sample carrier. |
| Reagent
lines |
BM/Hitachi
System Reagents |
Broad
range of reagent kits especially designed for use on Hitachi systems: 704, 705, 717, 737,
747, 902, 904, 911, 912, 917 and MODULAR. Includes assays for specific proteins, drugs of
abuse, therapeutic drug monitoring, enzymes, substrates, electrolytes and thyroid
hormones. |
| Reagent
lines |
COBAS
INTEGRA Reagents |
All
reagents for each test are packaged in a unique cassette, that the operator simply places
into the system. The same reagents are used by both the COBAS INTEGRA 700 and the COBAS
INTEGRA 400. Over 130 tests and applications for specific proteins, drugs of abuse,
therapeutic drug monitoring, enzymes, substrates, electrolytes and thyroid hormones. |
| Reagent
lines |
Multi-Purpose
Reagents (MPR) |
Reagent
kits for substrates, enzymes, inorganic ions and electrolytes. |
| Reagent
lines |
Calibrators
and Controls |
Range of
calibrators (Preciset, Precimat) for system standardisation and universal controls
(Precinorm, Precipath) for accuracy and precision monitoring. Common calibrators and
controls. |
| Reagent
lines |
Tina-quant(a) |
Reagents
for rheuma/autoimmune-testing, anaemia, proteins, cardiac tests, chronic alcohol abuse
test, lipid testing and therapeutic drug monitoring. |
| Reagent
lines |
ABUSCREEN
ONLINE |
A
comprehensive range of reagents for drugs of abuse testing using KIMS technology (Kinetic
Interaction of Microparticles in Solution). |
| Elecsys
line |
Elecsys
1010 |
Compact,
sample selective, multi-batch, bench top heterogeneous immunoassay analyser, designed for
low to medium workloads. Capacity of six tests onboard; up to 60 tests per hour. |
| Elecsys
line |
Elecsys
2010 |
Mid-size,
random and continuous access, bench top heterogeneous immunoassay analyser, designed for
medium workloads, with rapid STAT and turnaround time. Capacity of 12 tests onboard; up to
85 tests per hour. Sample carrier options include disc or Hitachi 5-position rack. |
| Elecsys
line |
Elecsys
Reagents |
Broad
range of assays for oncology, thyroid, fertility, anaemia and cardiac markers used on the
Elecsys systems. Based on ECL (electrochemiluminescence) detection technology. |
| COBAS
CORE line |
COBAS
CORE II |
Random
and continuous access, bench top, heterogeneous immunoassay analyser with STAT request
capabilities. Capacity of up to 18 tests onboard; up to 150 tests per hour. |
| COBAS
CORE line |
COBAS
CORE Reagents |
Extensive
line of assays covering oncology, retrovirus, hepatitis, TORCH, thyroid, fertility and H.
pylori tests. |
| Coagulation
line |
BM/STAGO
STA R |
Similar
to STA analyser, using BM/Hitachi 5-position racks as sample carrier, continuous loading.
210 sample positions, 200 different methods, 50 reagents onboard. Capacity of 350
tests/hour. Windows NT user-interface. |
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